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Status Quo of International Cooperation in Competitive Industries and Manufacturing in the Six Economic Corridors along the Belt and Road

Tang Yongchuan,Pan Yunhe, Zhang Xue, Hang Jiangjie

Strategic Study of CAE 2019, Volume 21, Issue 4,   Pages 60-68 doi: 10.15302/J-SSCAE-2019.04.003

Abstract: Comtrade Database, this paper focuses on the six economic corridors of the Belt and Road, and uses the revealedcomparative advantage index to comprehensively analyze the comparative industries in these countries

Keywords： the Belt and Road，manufacturing，six economic corridors，revealed comparative advantage index，multidimensional    

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Comparative transcriptomics revealed enhanced light responses, energy transport and storage in domestication

Zhiqiang XIA,Xin CHEN,Cheng LU,Meiling ZOU,Shujuan WANG,Yang ZHANG,Kun PAN,Xincheng ZHOU,Haiyan WANG,Wenquan WANG

Frontiers of Agricultural Science and Engineering 2016, Volume 3, Issue 4,   Pages 295-307 doi: 10.15302/J-FASE-2016126

Abstract: Co-expression networks among the pathways in each organs revealed the relationship of the genes involved

Keywords： cassava     comparative transcriptomics     energy transport     photosynthesis     starch synthesis    

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Multi-omics joint analysis revealed the metabolic profile of retroperitoneal liposarcoma

Frontiers of Medicine doi: 10.1007/s11684-023-1020-z

Abstract: Data analysis mainly revealed that glycolysis, purine metabolism, pyrimidine metabolism and phospholipid

Keywords： RLPS     proteomics     metabolomics     lipidomics     metabolism    

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HOW MULTISPECIES INTERCROP ADVANTAGE RESPONDS TO WATER STRESS: A YIELD-COMPONENT ECOLOGICAL FRAMEWORK

Frontiers of Agricultural Science and Engineering 2021, Volume 8, Issue 3,   Pages 416-431 doi: 10.15302/J-FASE-2021412

Abstract: We propose a relative multicrop resistance (RMR) index that captures all possible scenarios of absolute

Keywords： agroecosystem sustainability     crop overyielding     intercrop drought resistance     overyield ecological components    

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Strategy on the Development of Energy “Golden Triangle” Erea

The Research Group of “Strategic Research on the Development of Energy ‘Golden Triangle’ Erea”

Strategic Study of CAE 2015, Volume 17, Issue 9,   Pages 18-28

Abstract: This paper elaborates the regional developing situation and comparative advantages on the development

Keywords： energy “golden triangle”     comparative advantage     strategic opportunity     ecosystem     sustainable development    

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Taking advantage of drug resistance, a new approach in the war on cancer

Liqin Wang, Rene Bernards

Frontiers of Medicine 2018, Volume 12, Issue 4,   Pages 490-495 doi: 10.1007/s11684-018-0647-7

Abstract: combinations that are designed to avoid drug resistance, we discuss here therapeutic approaches that take advantage

Keywords： cancer     drug resistance     genetic screens     senescence     targeted therapy    

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Effect of ligand chain length on hydrophobic charge induction chromatography revealed by molecular dynamics

Lin ZHANG, Yan SUN

Frontiers of Chemical Science and Engineering 2013, Volume 7, Issue 4,   Pages 456-463 doi: 10.1007/s11705-013-1357-y

Abstract: Hydrophobic charge induction chromatography (HCIC) is a mixed-mode chromatography which is advantageous for high adsorption capacity and facile elution. The effect of the ligand chain length on protein behavior in HCIC was studied. A coarse-grain adsorbent pore model established in an earlier work was modified to construct adsorbents with different chain lengths, including one with shorter ligands (CL2) and one with longer ligands (CL4). The adsorption, desorption, and conformational transition of the proteins with CL2 and CL4 were examined using molecular dynamics simulations. The ligand chain length has a significant effect on both the probability and the irreversibility of the adsorption/desorption. Longer ligands reduced the energy barrier of adsorption, leading to stronger and more irreversible adsorption, as well as a little more unfolding of the protein. The simulation results elucidated the effect of the ligand chain length, which is beneficial for the rational design of adsorbents and parameter optimization for high-performance HCIC.

Keywords： adsorption     desorption     irreversibility     protein conformational transition     molecular dynamics simulation    

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Quantitative proteomics revealed extensive microenvironmental changes after stem cell transplantation

Frontiers of Medicine 2022, Volume 16, Issue 3,   Pages 429-441 doi: 10.1007/s11684-021-0842-9

Abstract: The local microenvironment is essential to stem cell-based therapy for ischemic stroke, and spatiotemporal changes of the microenvironment in the pathological process provide vital clues for understanding the therapeutic mechanisms. However, relevant studies on microenvironmental changes were mainly confined in the acute phase of stroke, and long-term changes remain unclear. This study aimed to investigate the microenvironmental changes in the subacute and chronic phases of ischemic stroke after stem cell transplantation. Herein, induced pluripotent stem cells (iPSCs) and neural stem cells (NSCs) were transplanted into the ischemic brain established by middle cerebral artery occlusion surgery. Positron emission tomography imaging and neurological tests were applied to evaluate the metabolic and neurofunctional alterations of rats transplanted with stem cells. Quantitative proteomics was employed to investigate the protein expression profiles in iPSCs-transplanted brain in the subacute and chronic phases of stroke. Compared with NSCs-transplanted rats, significantly increased glucose metabolism and neurofunctional scores were observed in iPSCs-transplanted rats. Subsequent proteomic data of iPSCs-transplanted rats identified a total of 39 differentially expressed proteins in the subacute and chronic phases, which are involved in various ischemic stroke-related biological processes, including neuronal survival, axonal remodeling, antioxidative stress, and mitochondrial function restoration. Taken together, our study indicated that iPSCs have a positive therapeutic effect in ischemic stroke and emphasized the wide-ranging microenvironmental changes in the subacute and chronic phases.

Keywords： ischemic stroke     microenvironment     induced pluripotent stem cells (iPSCs)     positron emission tomography (PET)     quantitative proteomics    

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Distinct immune escape and microenvironment between RG-like and pri-OPC-like glioma revealed by single-cell

Frontiers of Medicine doi: 10.1007/s11684-023-1017-7

Abstract: The association of neurogenesis and gliogenesis with glioma remains unclear. By conducting single-cell RNA-seq analyses on 26 gliomas, we reported their classification into primitive oligodendrocyte precursor cell (pri-OPC)-like and radial glia (RG)-like tumors and validated it in a public cohort and TCGA glioma. The RG-like tumors exhibited wild-type isocitrate dehydrogenase and tended to carry EGFR mutations, and the pri-OPC-like ones were prone to carrying TP53 mutations. Tumor subclones only in pri-OPC-like tumors showed substantially down-regulated MHC-I genes, suggesting their distinct immune evasion programs. Furthermore, the two subgroups appeared to extensively modulate glioma-infiltrating lymphocytes in distinct manners. Some specific genes not expressed in normal immune cells were found in glioma-infiltrating lymphocytes. For example, glial/glioma stem cell markers OLIG1/PTPRZ1 and B cell-specific receptors IGLC2/IGKC were expressed in pri-OPC-like and RG-like glioma-infiltrating lymphocytes, respectively. Their expression was positively correlated with those of immune checkpoint genes (e.g., LGALS3) and poor survivals as validated by the increased expression of LGALS3 upon IGKC overexpression in Jurkat cells. This finding indicated a potential inhibitory role in tumor-infiltrating lymphocytes and could provide a new way of cancer immune evasion.

Keywords： single-cell RNA-seq     glioma     radial glia     primitive oligodendrocyte precursor cell     immune escape    

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Microbial community dynamics at high organic loading rates revealed by pyrosequencing during sugar refinery

Liguo Zhang, Qiaoying Ban, Jianzheng Li

Frontiers of Environmental Science & Engineering 2018, Volume 12, Issue 4, doi: 10.1007/s11783-018-1045-8

Abstract:

High strength sugar refinery wastewater was treated in a mesophilic UASB.

Pyrosequencing reveals microbial community succession with OLR increase.

Diversity of microbial communities in OLR12 is much higher than those in OLR36 and OLR54.0 kgCOD/(kg VSS·d).

Fermentative bacteria could deal with increasing OLR through the increase of microbial diversity and quantity.

Hydrogen-producing acotogens and methanogens mainly coped with high OLR shocks by increasing the quantity of community

Keywords： Upflow anaerobic sludge blanket     Sugar refinery wastewater     Organic loading rate     Pyrosequencing     Microbial community structure    

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Changes of microbial composition during wastewater reclamation and distribution systems revealed by high-throughput

Yiwen LIN,Dan LI,Siyu ZENG,Miao HE

Frontiers of Environmental Science & Engineering 2016, Volume 10, Issue 3,   Pages 539-547 doi: 10.1007/s11783-016-0830-5

Abstract: The Chao index and Shannon diversity index showed that the diversities of microbial communities decreased

Keywords： wastewater reclamation systems     microbial community     pathogenic community     454-pyrosequencing    

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China’s new problems of food security revealed by the Food Equivalent Unit

Huilong LIN,Ruichao LI,Cangyu JIN,Chong WANG,Maohong WEI,Jizhou REN

Frontiers of Agricultural Science and Engineering 2014, Volume 1, Issue 1,   Pages 69-76 doi: 10.15302/J-FASE-2014023

Abstract: The discordance of the spatial distribution of water resource and virtual water revealed that China’s

Keywords： food security     nutrition security     food equivalent unit     grassland agriculture     China    

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EXPLORING THE RELATIVE ADVANTAGES OF LOCAL INNOVATION IN AGROFORESTRY

Frontiers of Agricultural Science and Engineering 2023, Volume 10, Issue 1,   Pages 61-72 doi: 10.15302/J-FASE-2022476

Abstract:

● Promotion of local sustainable innovation developed by forest farmers.

Keywords： agroforestry     forest farmers     local innovation     relative advantage     social forestry    

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The Development and Comparative Analysis of Engineering Project Management Modes

Ji-wei Zhu,Li-nan Zhou,Ming-yuan Yu,Zhao Zhai

Frontiers of Engineering Management 2015, Volume 2, Issue 4,   Pages 351-358 doi: 10.15302/J-FEM-2015060

Abstract: These have led to comparative analysis and brief commentary.

Keywords： engineering projects     management mode     comparative analysis     development trend    

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Comparative lipidomic analysis of

Bin QIAO, Hong-Chi TIAN, Ying-Jin YUAN

Frontiers of Chemical Science and Engineering 2012, Volume 6, Issue 4,   Pages 461-469 doi: 10.1007/s11705-012-1223-3

Abstract: A comparative lipidomic method was used to investigate the changes in total cellular PLs during continuous

Keywords： lipidomics     systems biology     phospholipids     stirred-tank     saccharomyces cerevisiae     biorefinery engineering    

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Title Author Date Type Operation

Status Quo of International Cooperation in Competitive Industries and Manufacturing in the Six Economic Corridors along the Belt and Road

Tang Yongchuan,Pan Yunhe, Zhang Xue, Hang Jiangjie

Journal Article

Comparative transcriptomics revealed enhanced light responses, energy transport and storage in domestication

Zhiqiang XIA,Xin CHEN,Cheng LU,Meiling ZOU,Shujuan WANG,Yang ZHANG,Kun PAN,Xincheng ZHOU,Haiyan WANG,Wenquan WANG

Journal Article

Multi-omics joint analysis revealed the metabolic profile of retroperitoneal liposarcoma

Journal Article

HOW MULTISPECIES INTERCROP ADVANTAGE RESPONDS TO WATER STRESS: A YIELD-COMPONENT ECOLOGICAL FRAMEWORK

Journal Article

Strategy on the Development of Energy “Golden Triangle” Erea

The Research Group of “Strategic Research on the Development of Energy ‘Golden Triangle’ Erea”

Journal Article

Taking advantage of drug resistance, a new approach in the war on cancer

Liqin Wang, Rene Bernards

Journal Article

Effect of ligand chain length on hydrophobic charge induction chromatography revealed by molecular dynamics

Lin ZHANG, Yan SUN

Journal Article

Quantitative proteomics revealed extensive microenvironmental changes after stem cell transplantation

Journal Article

Distinct immune escape and microenvironment between RG-like and pri-OPC-like glioma revealed by single-cell

Journal Article

Microbial community dynamics at high organic loading rates revealed by pyrosequencing during sugar refinery

Liguo Zhang, Qiaoying Ban, Jianzheng Li

Journal Article

Changes of microbial composition during wastewater reclamation and distribution systems revealed by high-throughput

Yiwen LIN,Dan LI,Siyu ZENG,Miao HE

Journal Article

China’s new problems of food security revealed by the Food Equivalent Unit

Huilong LIN,Ruichao LI,Cangyu JIN,Chong WANG,Maohong WEI,Jizhou REN

Journal Article

EXPLORING THE RELATIVE ADVANTAGES OF LOCAL INNOVATION IN AGROFORESTRY

Journal Article

The Development and Comparative Analysis of Engineering Project Management Modes

Ji-wei Zhu,Li-nan Zhou,Ming-yuan Yu,Zhao Zhai

Journal Article

Comparative lipidomic analysis of

Bin QIAO, Hong-Chi TIAN, Ying-Jin YUAN

Journal Article